Sample Mining and Data Mining: Combined Real-Time and Retrospective Approaches for the Identification of Emerging Novel Psychoactive Substances

Novel psychoactive substances (NPS) are synthetic drugs that pose serious public health and safety concerns. A multitude of NPS have been identified in the United States, often implicated in forensic investigations. The most common and effective manner for identifying NPS is by use of mass spectrometry and the true utility lies within nontargeted acquisition techniques. During this study, a liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) assay was developed, validated, and implemented for forensic toxicology testing. A SCIEX TripleTOF™ 5600 + with SWATH^® acquisition was used. Resulting data were compared against an extensive library database containing more than 800 compounds. The LC-QTOF-MS assay was applied to the reanalysis of biological sample extracts to discover emergent NPS. More than 3,000 sample extracts were analyzed, and more than 20 emerging NPS were detected for the first time. Among these were isopropyl-U-47700, 3,4-methylenedioxy-U-47700, fluorofuranylfentanyl, N-methyl norfentanyl, 2F-deschloroketamine, 3,4-methylenedioxy-alpha-PHP, eutylone, and N-ethyl hexedrone.     

新时代中国特色社会主义语境中的服务型政府建设

党的十九大报告中已经明确提出了要大力加强“建设人民满意的服务型政府”,为此,新时代中国特色社会主义对服务型政府建设提出了新的建设要求与总体目标。从新时代的语境中加以分析,发现如今服务型政府建设还有许多不满足新要求的问题,主要体现在政府的服务范围、服务理念、服务主体和服务供给机制等方面。针对上述几方面存在的问题,可以从明确服务边界、牢固树立服务行政理念、加强服务队伍建设、形成以人民需求为导向的公共服务供给机制等方面来加以探讨。     

大数据时代日本个人信息保护法探究

个人信息本来是极其隐私的事物,在大数据时代却时刻处于"裸奔"状态,时刻面临被侵犯的风险。特别在新冠肺炎疫情防控中,大数据技术发挥了重要作用,个人信息保护再次引起关注。整体而言,日本个人信息保护法以"个人优先"与"公共优先"的宗旨博弈为出发点,以"个人信息"的概念界定为基础,以个人信息权的保护为核心,以个人信息保护机构的独立设置为落脚点,为个人信息的保护奠定了基础。我国应当积极行动起来,尽快颁布《个人信息保护法》,助力大数据时代个人信息保护和数字经济的发展。     

我国高校政府采购存在的风险点及其管控

本文分析了我国高校在政府采购各环节中存在的风险点及高校政府采购的目标模式,并在此基础上提出完善政府采购制度、规范政府采购行为、健全采购监管机制、加强采购队伍建设、强化采购责任追究五个方面的风险管控措施,以期为我国高校政府采购提供借鉴。     

Peace Pedagogy and Interpretative Frameworks of Distrust: State–Society Relations in the Colombian Peace Process

The Havana Peace Accords of 2016 sought to end five decades of internal conflict in Colombia. As well as disarming the FARC, they promise to bring state institutions to abandoned regions and enable citizen participation. However, there is an obstacle to this which has consistently been overlooked by Juan Manuel Santos' government: a chronic distrust in the state dating back to colonialism. This article draws on ethnographic research with the Colombian government's ‘peace pedagogy’ team, tasked innovatively with educating citizens about the Havana Accords and incorporating them in the co-production of peace. It shows that citizens' learning about state policies, and reception of state efforts to shape that learning, are filtered through pre-existing perceptions of the state: in Colombia, interpretative frameworks of distrust. This ethnography illuminates state–society relations in the Colombian peace process, offering implications for ongoing implementation of the Accords, and posing questions for other countries in transition, arguing that historically-constituted perceptions of the state should be taken into account when communicating government policies to society.     

Local government projectification in practice – a multiple institutional logic perspective

ABSTRACT

During the last couple of decades, we have witnessed a proliferation of the project as an organizational solution in sectors as diverse as IT, housing, social services, education and culture. Despite a growing interest in the phenomenon, we know surprisingly little of how processes of public sector projectification unfold in practice, especially at local government level. This article uses an institutional logic perspective to illustrate and argue that public sector projectification can be understood and conceptualized as the enactment of multiple, co-existing institutional logics, but where one particular logic is of growing importance – the project logic. It is argued that even though the project form is often perceived as more flexible than that of the bureaucracy, the practical outcome seldom represents a radical break with traditional, bureaucratic management models. Rather, it appears to aid a rediscovery and reuse of central bureaucratic practices and procedures such as reporting, documentation and standardization.     

法学研究目标受众选择的大数据分析

文章为谁而写,是法学研究需要解决的基础性命题。从近二十年约2.5万篇法学核心期刊文章的大数据机器学习分类结果看,我国的法学研究成果呈多重目标格局,其中近三成服务于执法机关(包括行政机关和司法机关),同时也有为立法者、执政者建言献策的成果。经检验,目标受众类型的选择与论文的传播能力以及获得基金支持的机会之间有显著相关性。这一决定成果影响力大小的机制迟早会被个体习得并不断强化,成为研究者选择目标受众类型的重要因素。该机制良性运转的关键是处理好学者和实践受众的关系,保持学术研究必要的自主性,警惕学术研究在追逐发表、经济支持时被有关主体“认知俘获”。     

WTO背景下的政府政策体制分析

加入WTO将对我国政府的政策体制带来深刻的影响。目前政府政策体制存在着突出问题,我国政府应遵循政策体制改革与创新的原则,构建适应WTO要求的政策体制。     

廉政文化和先进家庭文化契合的长效机制探讨

反腐倡廉,理论指导和观念创新先行。追求廉政文化与先进家庭文化的契合,必须创新载体,采用多种途径;同时移植、借鉴国外在反腐败方面的有益经验,多元联动、综合整治,系统推进,建立长效机制,为构建和谐社会提供良好的政务、法制、体制环境与保障。     

CIS原理与政府形象设计

政府形象设计是政府形象管理的重要环节。借鉴CIS原理将企业CIS的设计和运作导入政府形象设计中,以政府行政理念为指导,通过提升政府行为和完善政府外在特征来提高政府在公众心目中的评价,把政府的理念、行为与视觉形象统一起来,使政府形象系统化。